The diagnosis of small cell lung cancer is usually apparent by routine microscopy. Other techniques that may be useful in selected cases, particularly when the diagnosis is in doubt, include electron microscopy, which detects the small cell cancer's neuroendocrine granules, and immunocytochemical stains, which can detect certain markers characteristic for small cell cancer. Newer techniques, still investigational, include examining the tumor DNA for chromosome abnormalities, overexpression of oncogenes and deletion of tumor suppressor genes.
Blood and Other Tests
• Chemistry profile.
• Sputum (phlegm) examination.
• Removal of fluid from the chest and examination of it for malignant cells .
